In Brief: Azmiro A Single-Dose Injectable Formulation of Testosterone Cypionate The Medical Letter Inc

In Brief: Azmiro A Single-Dose Injectable Formulation of Testosterone Cypionate The Medical Letter Inc

Testosterone may also be used for other conditions as determined by your health care provider. Androgens are responsible for the growth spurt of adolescence and for eventual termination of linear growth, brought about by fusion of the epiphyseal growth centers. In children, exogenous androgens accelerate linear growth rates, but may cause disproportionate advancement in bone maturation. Use over long periods may result in fusion of the epiphyseal growth centers and termination of the growth process. Androgens have been reported to stimulate production of red translate my blood test results cells by enhancing production of erythropoietic stimulation factor. Finally, in the present analysis it was attempted to select those studies of testosterone treatment that provided adequate doses/delivery of testosterone.

This medicine may cause edema (fluid and sodium retention). Check with your doctor right away if you have a decrease in amount of urine, swelling of the fingers, hands, feet, or lower legs, trouble breathing, or weight gain.

People who are interested in testosterone injections should speak with a knowledgeable doctor. They can advise on whether this is likely to help a person with potentially low testosterone or refer someone to a gender care specialist. If testosterone levels get too high, a person may have more serious symptoms, such as signs of liver toxicity. People can visit a doctor who will administer the injections into the buttocks, or they can self-administer the injection at home by inserting a needle into the thigh.

DEPO-Testosterone Injection contains testosterone, a Schedule III controlled substance in the Controlled Substances Act. The use of testosterone in women who are pregnant is contraindicated. Testosterone is known to cause virilization of the female fetus when administrated to pregnant women. Hypogonadotropic hypogonadism (congenital or acquired) – gonadotropin or LHRH deficiency, or pituitary-hypothalamic injury from tumors, trauma, or radiation.

Single-use packets containing 40.5mg of testosterone in alcohol-based gel OR metered-dose pump which dispenses 20.25mg of testosterone in alcohol-based gel pump. The usual starting dose is 1 packet or 4 pumps daily (about the size of 2 quarters) applied to shoulders, upper arms, and abdomen. Single-use packets containing 50mg of testosterone in 5g of alcohol-based gel OR metered-dose pump which dispenses 12.5mg of testosterone in 1.25g of alcohol-based gel per pump. The usual starting dose is 1 packet or 4 pumps daily (about the size of 2 quarters) applied to the shoulders, upper arms, and abdomen. Multiple topical testosterone products are available in both branded and generic form.

Low testosterone levels in males can lead to mood changes, difficulty concentrating, erectile dysfunction (trouble getting or keeping an erection), and low sex drive. It can also cause reduced growth of the penis and testicles, gynecomastia (breast growth), loss of body hair and muscle mass, anemia (low level of red blood cells), and osteoporosis (weakened bones). In addition, androgens have been linked to increased risk of heart disease, including congestive heart failure, heart attack and stroke. Appropriate studies on the relationship of age to the effects of testosterone cypionate injection have not been performed in the geriatric population. However, elderly patients are more likely to have heart or prostate problems (including enlarged prostate), which may require caution in patients receiving this medicine.

In diabetic patients, the metabolic effects of androgens may decrease blood glucose and, therefore, insulin requirements. Patients with benign prostatic hypertrophy may develop acute urethral obstruction. Oligospermia may occur after prolonged administration or excessive dosage. If any of these effects appear, the androgen should be stopped and if restarted, a lower dosage should be utilized.

The patient experiences, to his satisfaction, profound changes in his physical appearance and his mental makeup. The attending physician observes the changes the patient undergoes and rarely fails to be fascinated by the multitude of functions testosterone appears to have in the process of masculinization in the broadest sense (1). Talk with your doctor about other drug options that may work for you. Testosterone cypionate is given by injection into a muscle (usually the buttocks).

Free thyroid hormone levels remain unchanged, however, and there is no clinical evidence of thyroid dysfunction. Androgens may decrease levels of thyroxine­binding globulin, resulting in decreased total T4 serum levels and increased resin uptake of T3 and T4. The time-course for the spectrum of effects of testosterone may vary considerably, as testosterone actions are exerted through a cascade of many different pathways. Most of the actions of testosterone take place via the androgen receptor as a transcription factor activated by testosterone. Over the past two decades evidence of rapid responses to androgens, dependent or independent of the androgen receptor, occurring at the cellular and organ level has accumulated.

Do not share this medicine with anyone who has not been prescribed this medicine. Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine. Keep all appointments for medical exams and tests while on this medicine. If the liquid medicine has any particles in it, appears discolored, or if the vial appears damaged, do not use it. Read and make sure you understand the instructions for measuring your dose and using the syringe before using this medicine.